What happens when six key opinion leaders in eye care participate in a roundtable on the latest strategies for managing patients with dry eye disease? They produce a good primer on the topic, with pearls on working up new dry eye patients, factors that impact symptoms and formulation parameters to consider when evaluating artificial tears. In the following pages, these clinicians impart their knowledge and experience in the hopes of enhancing your interactions with dry eye patients, as well as those with meibomian gland dysfunction.