Study suggests this could be an important biomarker for early-stage detection of the disease.

It occurred within two months in approximately 25% of small, idiopathic FTMH and 55% of idiopathic FTMH with a diameter <150µm.

“Anastomosis and loops" and vessel density were useful to demonstrate change within a year in nonexudative eyes.

However, a related finding—shallow irregular RPE elevation—does not improve predictive ability.

The retinal nerve fiber and ganglion cell layers are both important in early detection of the disease.

A high posterior vitreous separation height may indicate greater risk for progression, especially among females.

Researchers pinpointed three SD-OCT features to identify patients at risk of greater VA decline: hyperreflectivity, pigment and EZ loss.