Although central serous chorioretinopathy (CSC) is a choroidal disorder, researchers recently observed retinal vascular alterations using OCT angiography (OCT-A).

The study evaluated 472 eyes of 336 patients with chronic CSC who underwent OCT-A. Each image was graded to assess for microvascular retinal alterations, including vascular rarefaction/retinal hypoperfusion, foveal avascular zone (FAZ) enlargement and the presence of telangiectasia or microaneurysms.

Of the 472 eyes imaged, OCT-A revealed microvascular retinal alterations in 18 eyes of 14 patients (3.6%). One eye had retinal telangiectasia, while 17 had areas of retinal vascular rarefactions and three had an enlarged FAZ. The team found that retinal vascular changes affected the parafoveal region the most (66.7%), followed by the foveal (22.2%) and perifoveal (11.1%) regions.