Eyelid wipes are routinely recommended for those with blepharitis, but researchers have pointed out that such wipes aren’t cheap and come with potential adverse effects. In a recent review study, researchers compiled a summary of existing evidence for the efficacy and safety of eyelid wipes for managing blepharitis.

The researchers reviewed 1,650 studies and included 16 that investigated eyelid wipes as a blepharitis intervention. The various options included common household products, tea tree oil-based products and commercial solutions and wipes. Most of the studies demonstrated some efficacy and reported improvement within one to two months; however, the researchers found significant heterogeneity among outcomes. They also noted that several studies were supported by the manufacturing company.

The researchers concluded that though some efficacy was demonstrated for several of the eyelid hygiene products—including common household products—there’s still a lack of robust evidence to support their routine recommendation, and no single product showed superiority over any other. “The long-term costs and potential adverse effects should not be overlooked,” they added.